Alexey, Project idea

Explore some of the mathematical models (if they exist) of how a cell chooses between 2 variants of way of activation. It is important for understanding the mechanism of platelet division into subpopulations during activation (GPIIaIIa-exposing and phosphatidylserine exposing platelets).

a)    simple ODE model of any cell’s choice performance (for example, in apoptosis, in proliferation, ect.)

b)   ­stochastic vs. ODE Ca2+-signaling model

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