Marc Fink, Student Project Idea

I am going to develop a model of acute resistance to the HER2 inhibitor, lapatinib, in breast cancer cells.  Upon inhibition of HER2 activity, cells up-regulate the levels of several receptor tyrosine kinases.  These RTKs promote survival signaling.  These events will be modeled and this will be used to explain resistance.

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One response to “Marc Fink, Student Project Idea

  1. Hi Marc,

    I am interested in working with you together. My original idea for the student project is modeling and analysis of allosteric inhibition of Taspase 1’s pathobiological activity [Carolin Bier etal. 2012]. Because I am not in Biology, it is quite difficult for me to understand the whole process and reactions. So now I am thinking about to work with you together. I am good at mathematics and analysis. Is it okay? Shall we talk?

    Best regards

    Yan

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