Project Proposal: Modeling cell cycle re-entry and differentiation – Tim van Mourik [Albert]

In the lab I work in it has been shown that terminally differentiated cells can be pushed back into the cell cycle without going back into an undifferentiated state. During my student project I would like to create a model for cell cycle re-entry and differentiation in a similar way as John Tyson has shown us for the cell cycle transitions. It would be nice to find out how these processes might interact and if it is also possible in the model to push differentiated cells back into the cell cycle.

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